Correction: Sustained Release of a Monoclonal Antibody from Electrochemically Prepared Mesoporous Silicon Oxide

Pore size is a critical parameter for obtaining sustained protein release from electrochemically synthesized mesoporous silicon microparticles

Mesoporous silicon has become a material of high interest for drug delivery due to its outstanding internal surface area and inherent biodegradability. We have previously reported the preparation of mesoporous silicon microparticles (MS-MPs) synthesized by an advantageous electrochemical method, and showed that due to their inner structure they can adsorb proteins in amounts exceeding the mass ...

Study of Mesoporous Silica Nanoparticles as Nanocarriers for Sustained Release of Curcumin

Curcumin (CUR) is a hydrophobic molecule and beneficial antioxidant with known anticancer property. The bioavailability of curcumin is low because of its hydrophobic structure. Mesoporous silica nanoparticles (MSN) loaded by CUR were used as nanocarriers for sustained release of CUR in four different media such as simulated gastric,intestinal, colon and body fluids (SGF, SIF, SCF, and SBF, ...

Electrochemically deposited gallium oxide nanostructures on silicon substrates

We report a synthesis of β-Ga2O3 nanostructures on Si substrate by electrochemical deposition using a mixture of Ga2O3, HCl, NH4OH, and H2O. The presence of Ga3+ ions contributed to the deposition of Ga2O3 nanostructures on the Si surface with the assistance of applied potentials. The morphologies of the grown structures strongly depended on the molarity of Ga2O3 and pH level of electrolyte. β-...

Sustained small interfering RNA delivery by mesoporous silicon particles.

RNA interference (RNAi) is a powerful approach for silencing genes associated with a variety of pathologic conditions; however, in vivo RNAi delivery has remained a major challenge due to lack of safe, efficient, and sustained systemic delivery. Here, we report on a novel approach to overcome these limitations using a multistage vector composed of mesoporous silicon particles (stage 1 micropart...

Development of a Novel Inhibitory Chimeric Anti-HER2 Monoclonal Antibody